One day, a patient came to me and said, Sir, I almost died. I was vaccinated against the flu, but my condition did not improve and I was taken to the hospital. Whatever it was, it was really scary. I advised: That's because of the vaccination. 



But the next year, the man came again and said, "I got the flu shot this year," he said. It sounds like a comical story, but when you are in a hospital, you actually experience these kinds of things often. Like a moth flying into the flames, There are too many people who run to doctors and lose their lives or shorten their lives.



The Japanese are the world's favorite people for hospitals. I visit the hospital on average 14 times a year, This number is more than double that of developed countries.

Health checkups and cancer screenings are also encouraged at the national level, so they are diligently tested.



“If you go to the hospital, what will the doctor do?” “Doctors are experts in diseases, so they will know how to prevent and treat them.” Most people trust and follow doctors without much thought, so even if they have had a near-death experience, they go to the doctor again.

작성

Cure of Diabetes

mi jung park
2022-01-18
조회수 1132199

In case of type 1 diabetes, insulin treatment is required. In the case of type 2 diabetes, lifestyle modification is the basis, and additional drug administration may be required. In the case of oral medicine, it is taken 1 to 3 times a day, and depending on the time of action of the medicine, the time taken and side effects are slightly different.


Oral hypoglycemic agents are largely divided into insulin secretagogues and insulin sensitivity improvers. Insulin secretagogues include sulfonylurea and meglitinide. Sulfonureas, a commonly prescribed drug, can cause hypoglycemic conditions. These include amaryl (ingredient: glimepiride), diamicron (ingredient: gliclazide), and daonyl (ingredient: glibenclamide).


Meglitinide, a type of insulin secretagogue, is a very fast-acting agent that is taken before meals. nide mitiglinide) and the like.


Insulin sensitivity improving agents are characterized by almost no hypoglycemia when taken alone, and include metformin, a biguanide-based drug, and Avandia (ingredient: rosiglitazone), a thiazolidinedione-based drug, and Actos ( Ingredient name: pioglitazone), etc. In addition, there are glucobai (ingredient name: acarbose) and Basin (ingredient name: voglibose) that delay carbohydrate absorption in the small intestine.


Meanwhile, there is a GLP-1 agonist developed using the action of GLP-1 (glucagon-like peptide-1; glucagon-like peptide-1), a hormone that lowers blood sugar, and exenatide and This includes injections such as liraglutide. In addition, a DPP-4 inhibitor that inhibits the action of DPP-4 (dipeptidyl peptidase-4; dipeptidyl peptidase-4), an enzyme that rapidly inactivates GLP-1, is also used, and Januvia (ingredient name: Sitagl) There are liptin sitagliptin), gabs (ingredient name: vildagliptin), and saxagliptin.


Recently developed new drugs include SGLT2 inhibitors that inhibit glucose reabsorption in the kidneys, and these are known to have an effect on preventing cardiovascular complications, but long-term side effects require follow-up.


Insulin is currently available as an injection, and in principle, it is administered by subcutaneous injection, and the method of administration differs depending on the time of action. It has a faster blood sugar lowering effect than oral medicines, can be used safely even in environments where oral medicines cannot be used, and has no dose limit, but disadvantages include rejection of needles and difficulty in administration.


Insulin is classified into super fast-acting, short-acting, intermediate-acting, and long-acting insulin depending on the duration of action. The detailed description is as follows.

Rapid-acting insulin begins to take effect within 15 minutes after administration, and the effect usually lasts 3 to 4 hours. Therefore, it is administered right after or just before a meal, and it is easy to control blood sugar after a meal. These include insulin lispro, insulin aspart, and insulin glulisine.


The fast-acting insulin is the insulin used to control postprandial blood sugar before the super fast-acting insulin was released, and regular insulin belongs to this category. It usually takes effect 30 minutes to 1 hour after administration, and the effect usually lasts 2 to 4 hours.


Intermediate-acting insulin (NPH insulin) has an effect 1 to 3 hours after administration, and the effect usually lasts 12 to 16 hours, and the highest effect is shown at 6 to 8 hours after administration. Insulin is characteristically cloudy.


Long-acting insulin includes insulin glargine, insulin detemir, and degludec, and is mainly used as basal insulin because of its longer action time and constant effect than intermediate-acting insulin. 

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